Reduced apoptotic response to camptothecin in CHO cells deficient in XRCC3
نویسندگان
چکیده
منابع مشابه
Reduced apoptotic response to camptothecin in CHO cells deficient in XRCC3.
Eukaryotic cells respond to DNA damage by activation of DNA repair, cell-cycle arrest and apoptosis. Several reports suggest that such responses may be coordinated by communication between damage repair proteins and proteins signalling other cellular responses. The Rad51-guided homologous recombination (HR) repair plays an important role in recognition and repair of DNA double-strand breaks (DS...
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ژورنال
عنوان ژورنال: Carcinogenesis
سال: 2003
ISSN: 1460-2180
DOI: 10.1093/carcin/24.2.249